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Case Reports
. 2012 Jun;27(2):224-8.
doi: 10.3904/kjim.2012.27.2.224. Epub 2012 May 31.

Angiosarcomas of the bilateral breast and heart: which one is the primary site?

Eun Kyoung Kim  1 , Ik-Soo Park, Byeong Seok Sohn, Jeong Eun Kim, Dae Ho Lee, Sang-We Kim, Cheolwon Suh
Affiliations
Case Reports

Angiosarcomas of the bilateral breast and heart: which one is the primary site?

Eun Kyoung Kim et al. Korean J Intern Med. 2012 Jun.

Abstract

A 29-year-old pregnant woman with recurrent pericardial effusion and a cardiac tumor, diagnosed as an angiosarcoma, was treated with surgical resection of the tumor followed by radiotherapy. Immediately after completion of radiotherapy, she developed bilateral breast masses, which were also confirmed as angiosarcomas. We thought this might be the first case of bilateral angiosarcoma of the breast metastasizing to heart mimicking a primary cardiac angiosarcoma, although we could not conclude with certainty that angiosarcoma of the heart was not the primary site.

Keywords: Breast; Heart; Hemangiosarcoma.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1
The echocardiography shows an intra-cardiac mass (arrow) in the anterior side of right atrial wall. (A) Modified parasternal view. (B) Apical four chamber view. RA, right atrium; RV, right ventricle; LA, left atrium; RV, left ventricle.
Figure 2
Figure 2
The magnetic resonance imaging of the heart shows an intra-cardiac mass (arrow) in the anterior side of the right atrial wall encasing a right coronary artery.
Figure 3
Figure 3
The positron emission tomography shows hypermetabolic lesions in both breast masses (arrows).
Figure 4
Figure 4
The pathology of the cardiac tumor confirms angiosarcoma with vasoformitive architectures. (A) H&E, × 200. (B) H&E, × 400.
Figure 5
Figure 5
Serial computed tomography shows the bilateral breast masses (arrows).
Figure 6
Figure 6
The pathology of the breast masses reveals spindle cell sarcoma similar to previous angiosarcoma of the heart. (A) Pap, × 100. (B) Pap, × 400.
See this image and copyright information in PMC

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