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. 2012 Jun;9(2):127-33.
doi: 10.4306/pi.2012.9.2.127. Epub 2012 Apr 2.

Determinants of quality of life in the acute stage following stroke

Bo-Ok Jeong  1 , Hee-Ju Kang, Kyung-Yeol Bae, Sung-Wan Kim, Jae-Min Kim, Il-Seon Shin, Joon-Tae Kim, Man-Seok Park, Ki-Hyun Cho, Jin-Sang Yoon
Affiliations

Determinants of quality of life in the acute stage following stroke

Bo-Ok Jeong et al. Psychiatry Investig. 2012 Jun.

Abstract

Objective: This study aimed to investigate the factors influence the quality of life (QOL) of survivors of an acute stroke.

Methods: For 422 stroke patients, assessments were made within two weeks of the index event. QOL was measured using the World Health Organization Quality of Life-Abbreviated form (WHOQOL-BREF), which has four domains related to physical factors, psychological factors, social relationships, and environmental context. Associations of each four WHOQOL-BREF domain score with socio-demographic characteristics (age, sex, education, marital status, religion, and occupation), stroke severity (National Institutes of Health Stroke Scale), physical disability (Barthel Index), cognitive function (Mini-Mental Status Examination: MMSE), grip strength, and psychological distress (Hospital Anxiety and Depression Scale depression and anxiety subscale: HADS-D and HADS-A) were investigated using the linear regression models.

Results: Higher physical domain scores were independently associated with higher MMSE scores, stronger hand-grip strength, and lower HADS-D and HADS-A scores; higher psychological domain scores were independently associated with higher educational level, higher MMSE scores, and lower HADS-D and HADS-A scores; higher social relationships domain scores were independently associated with lower HADS-D and HADS-A scores; and higher environmental domain scores were independently associated with higher educational level, higher MMSE scores, and lower HADS-D scores.

Conclusion: Psychological distress and impaired cognitive function were independently associated with lower QOL in patients with acute stroke. However, stroke severity, physical disability and other socio-demographic factors were less significantly associated with QOL. These findings underscore the importance of psychological interventions for improving QOL during the acute phase following stroke.

Keywords: Anxiety; Cognitive function; Depression; Quality of life; Stroke.

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