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. 2012 Jul;18(7):1144-6.
doi: 10.3201/eid1807.120009.

Human infection from avian-like influenza A (H1N1) viruses in pigs, China

Huanliang Yang  1 , Chuanling Qiao, Xu Tang, Yan Chen, Xiaoguang Xin, Hualan Chen
Affiliations

Human infection from avian-like influenza A (H1N1) viruses in pigs, China

Huanliang Yang et al. Emerg Infect Dis. 2012 Jul.

Abstract

In investigating influenza in an immunodeficient child in China, in December 2010, we found that the influenza virus showed high sequence identity to that of swine. Serologic evidence indicated that viral persistence in pigs was the source of infection. Continued surveillance of pigs and systemic analysis of swine influenza isolates are needed.

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Figures

Figure 1
Figure 1
Phylogenetic tree of selected swine, human, and avian H1 hemagglutinin 1 sequences. An unrooted phylogenetic tree was generated by the distance-based maximum-likelihood method by using MEGA5 software (www.megasoftware.net). Bootstrap values were calculated on the basis of 1,000 replications; A/swine/Jiangsu/40/2011 is in boldface. Scale bar indicates nucleotide substitutions per site.
Figure 2
Figure 2
Multiple alignment of hemagglutinin protein sequences. Epitopes Sa, Sb, Ca1, Ca2, and Cb are indicated. Triangle, Sa; circle, Sb; square, Ca1; hexagon, Ca2; diamond, Cb. Putative glycosylation sites are indicated in blue-lined boxes.
See this image and copyright information in PMC

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