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Comment
. 2012 Jun 26;109(26):10128-9.
doi: 10.1073/pnas.1207725109. Epub 2012 Jun 18.

A massively spectacular view of the chemical lives of microbes

Matthew F Traxler  1 , Roberto Kolter
Affiliations
Comment

A massively spectacular view of the chemical lives of microbes

Matthew F Traxler et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
NanoDESI MS workflow. (A) NanoDESI allows for direct sampling of almost any surface (biotic or otherwise), including bacterial colonies, plants, and animals. (B) Solvent is pumped onto and then off of the sample surface and subsequently electrosprayed into the mass spectrometer. Ions of individual parent mass are fragmented yielding hundred or thousands of tandem mass spectra. (C) Parent masses represented as nodes are built into networks based on MS2 spectral similarity, allowing for analysis of individual compounds within the context of the entire chemical profile.
See this image and copyright information in PMC

Comment on

  • Mass spectral molecular networking of living microbial colonies.
    Watrous J, Roach P, Alexandrov T, Heath BS, Yang JY, Kersten RD, van der Voort M, Pogliano K, Gross H, Raaijmakers JM, Moore BS, Laskin J, Bandeira N, Dorrestein PC. Watrous J, et al. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):E1743-52. doi: 10.1073/pnas.1203689109. Epub 2012 May 14. Proc Natl Acad Sci U S A. 2012. PMID: 22586093 Free PMC article.

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