Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012:4:12.
doi: 10.3410/M4-12. Epub 2012 Jun 1.

New drugs to treat tuberculosis

Susan Swindells  1
Affiliations

New drugs to treat tuberculosis

Susan Swindells. F1000 Med Rep. 2012.

Abstract

Tuberculosis (TB) has been a leading cause of death for more than a century. While effective therapies exist, treatment is long and cumbersome. Tuberculosis control is complicated by the overlapping problems created by global inadequacy of public health infrastructures, the interaction of the TB and human immunodeficiency virus epidemics, and the emergence of drug-resistant TB. After a long period of neglect, there is now significant progress in development of TB diagnostics and therapeutics. Focusing on treatment for active TB, we review the new pathways to TB regimen development, and the new and repurposed anti-TB agents in clinical development.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.. Timeline for TB drug development
Major milestones in TB treatment over the last century are outlined by the date of approval of the drug or intervention. Approval dates for drugs in development are estimated.
See this image and copyright information in PMC

References

    1. Global Tuberculosis Control 2011. http://www.who.int/tb/publications/global_report/en/index.html
    1. The World Health Report 2004. http://www.who.int/whr/2004/annex/topic/en/annex_2_en.pdf
    1. 2009 Tuberculosis and Women. http://www.who.int/tb/challenges/gender/factsheet_womenandtb.pdf
    1. HIV and TB. http://www.cdc.gov/hiv/resources/factsheets/PDF/hivtb.pdf
    1. Young DB, Perkins MD, Duncan K, Barry CE. Confronting the scientific obstacles to global control of tuberculosis. J. Clin. Invest. 2008;118:1255–65. doi: 10.1172/JCI34614. - DOI - PMC - PubMed

    2. F1000 Factor 6

      Evaluated by Susan Swindells 17 May 2012