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Review
. 1990 Sep;17(2-3):373-8.
doi: 10.1016/0305-7372(90)90071-m.

Antibody targeted therapy in cancer: comparison of murine and clinical studies

R H Begent  1 , R B Pedley
Affiliations
Review

Antibody targeted therapy in cancer: comparison of murine and clinical studies

R H Begent et al. Cancer Treat Rev. 1990 Sep.

Abstract

Antibody targeted therapy can be effective in animal models of cancer. Treatment has been less successful in man, though some responses are reported. Understanding the distribution of antibody in man and animals shows how toxicity may be minimized and patients selected for therapy on the basis of efficient antibody localization in the tumour.

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