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Comment
. 2012 Jun 22;12(7):447.
doi: 10.1038/nrc3304.

Metastasis. Exosomes drive premetastatic niche formation

Gemma K Alderton
Comment

Metastasis. Exosomes drive premetastatic niche formation

Gemma K Alderton. Nat Rev Cancer. .

Abstract

Peinado and colleagues find that exosomes produced by tumour cells can mediate premetastatic niche formation.

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Comment on

  • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
    Peinado H, Alečković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D. Peinado H, et al. Nat Med. 2012 Jun;18(6):883-91. doi: 10.1038/nm.2753. Nat Med. 2012. PMID: 22635005 Free PMC article.

References

    1. Nat Med. 2012 Jun;18(6):883-91 - PubMed

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