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Comment
. 2012 Jun 22;12(7):450-1.
doi: 10.1038/nrc3307.

Tumorigenesis. Better by half

Nicola McCarthy
Comment

Tumorigenesis. Better by half

Nicola McCarthy. Nat Rev Cancer. .

Abstract

This paper suggests that recurrent regions of somatic hemizygosity might exist in tumours because they enable a reduction in the expression levels of genes that restrict cell proliferation and survival, and minimize the loss of genes that are essential for cell survival.

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References

    1. Science. 2012 Jul 6;337(6090):104-9 - PubMed

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