Stem cells. Antipsychotic to anticancer agent?

Comment

Darren J Burgess. Nat Rev Cancer. 2012.

. 2012 Jun 22;12(7):452-3.

doi: 10.1038/nrc3305.

Abstract

A new study shows that a clinically approved drug might selectively target cancer stem cells for differentiation.

Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.
Sachlos E, Risueño RM, Laronde S, Shapovalova Z, Lee JH, Russell J, Malig M, McNicol JD, Fiebig-Comyn A, Graham M, Levadoux-Martin M, Lee JB, Giacomelli AO, Hassell JA, Fischer-Russell D, Trus MR, Foley R, Leber B, Xenocostas A, Brown ED, Collins TJ, Bhatia M. Sachlos E, et al. Cell. 2012 Jun 8;149(6):1284-97. doi: 10.1016/j.cell.2012.03.049. Epub 2012 May 24. Cell. 2012. PMID: 22632761