Genomic instability. Mutagenic clusters
- PMID: 22722398
- DOI: 10.1038/nrc3306
Genomic instability. Mutagenic clusters
Abstract
Gordenin and colleagues analyse the clustering of mutations in cancer genomes and identify a subfamily of APOBECs as a possible cause of mutation clustering.
Comment on
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Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.Mol Cell. 2012 May 25;46(4):424-35. doi: 10.1016/j.molcel.2012.03.030. Epub 2012 May 17. Mol Cell. 2012. PMID: 22607975 Free PMC article.
References
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- Mol Cell. 2012 May 25;46(4):424-35 - PubMed
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