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Comment
. 2012 Jun 22;336(6088):1506; author reply 1506.
doi: 10.1126/science.1221434.

Comment on "Seroevidence for H5N1 influenza infections in humans: meta-analysis"

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Comment

Comment on "Seroevidence for H5N1 influenza infections in humans: meta-analysis"

Maria D Van Kerkhove et al. Science. .

Abstract

A better understanding of the severity of H5N1 in humans is needed. Wang et al. (Brevia, 23 March 2012, p. 1463; published online 23 February 2012) overinterpret the results of seroprevalence studies and take too little account of underlying uncertainties. Although the true risk of death from H5N1 infection will likely be lower than the 60% of reported laboratory-confirmed cases, there is little evidence of millions of missed infections.

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