doi: 10.1017/s0016672300035205.
Sex chromosome configurations in pachytene spermatocytes of an XYY mouse
Affiliations
- PMID: 2272502
- DOI: 10.1017/s0016672300035205
Item in Clipboard
Sex chromosome configurations in pachytene spermatocytes of an XYY mouse
Genet Res.
1990 Oct-Dec.
Abstract
Karyotypic investigation of a phenotypically normal but sterile male mouse showed the presence of an XYY sex chromosome constitution. The synaptic behaviour of the three sex chromosomes was examined in 65 pachytene cells. The sex chromosomes formed a variety of synaptic configurations: an XYY trivalent (40%); an XY bivalent and Y univalent (38.5%); an X univalent and YY bivalent (13.8%); or X, Y, Y univalence (7.7%). There was considerable variation in the extent of synapsis and some of the associations clearly involved nonhomologous pairing. These observations have been compared with previously published information on chromosome configurations at metaphase I from other XYY males.
Similar articles
-
The prevalence of a YY synaptonemal complex over XY synapsis in an XYY man with exclusive XYY spermatocytes.Chromosome Res. 1997 Nov;5(7):467-74. doi: 10.1023/a:1018469030537. Chromosome Res. 1997. PMID: 9421264
-
XYY spermatogenesis in XO/XY/XYY mosaic mice.Cytogenet Cell Genet. 1990;54(1-2):29-34. doi: 10.1159/000132949. Cytogenet Cell Genet. 1990. PMID: 2249471
-
Selective advantage of euploid spermatocytes I in an azoospermic 47,XYY man with gonadal mosaicism.Hum Reprod. 2019 Mar 1;34(3):568-573. doi: 10.1093/humrep/dey387. Hum Reprod. 2019. PMID: 30597018
-
Meiotic segregation of sex chromosomes in mosaic and non-mosaic XYY males: case reports and review of the literature.Int J Androl. 2003 Aug;26(4):242-9. doi: 10.1046/j.1365-2605.2003.00421.x. Int J Androl. 2003. PMID: 12846800 Review.
-
Phenotype/karyotype correlations of Y chromosome aneuploidy with emphasis on structural aberrations in postnatally diagnosed cases.Am J Med Genet. 1994 Nov 1;53(2):108-40. doi: 10.1002/ajmg.1320530204. Am J Med Genet. 1994. PMID: 7856637 Review.
Cited by
-
Persistence of two Y chromosomes through meiotic prophase and metaphase I in an XYY man.Hum Genet. 1991 Aug;87(4):416-20. doi: 10.1007/BF00197159. Hum Genet. 1991. PMID: 1879828
-
Increased incidence of hyperhaploid 24,XY spermatozoa detected by three-colour FISH in a 46,XY/47,XXY male.Hum Genet. 1996 Feb;97(2):171-5. doi: 10.1007/BF02265260. Hum Genet. 1996. PMID: 8566948
-
The prevalence of a YY synaptonemal complex over XY synapsis in an XYY man with exclusive XYY spermatocytes.Chromosome Res. 1997 Nov;5(7):467-74. doi: 10.1023/a:1018469030537. Chromosome Res. 1997. PMID: 9421264