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Comparative Study
. 2012 Dec;54(6):770-2.
doi: 10.1111/j.1442-200X.2012.03692.x. Epub 2012 Oct 8.

Incidence of Kawasaki disease in northern European countries

Affiliations
Comparative Study

Incidence of Kawasaki disease in northern European countries

Eeva Salo et al. Pediatr Int. 2012 Dec.

Abstract

Background: The aim of the present study was to compare the epidemiologic features of Kawasaki disease (KD) in three northern European countries and Japan.

Methods: Data were obtained from discharge databases for hospitals in Finland, Norway, and Sweden for 1999-2009 and from nationwide epidemiologic surveys in Japan for 1998-2008. Annual incidence for each country was calculated using regional census data.

Results: During the 11 year period, 1390 KD patients were recorded in the registries of the three northern European countries. Average annual incidence rates per 100,000 children aged <5 years were: Finland, 11.4; Norway, 5.4; and Sweden, 7.4. Overall, 86.4% of Japanese KD patients were aged <5 years compared to only 67.8% in the four northern European countries (P < 0.001).

Conclusions: The incidence of KD in northern Europe was constant over the study period and much lower than in Japan. There was a significant age difference between northern European and Japanese KD patients that remains unexplained.

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Conflict of interest statement

COMPETING INTERESTS

None to declare.

Figures

Figure 1
Figure 1
Annual incidence of Kawasaki disease in Northern European countries from 1999–2009 expressed as number of cases per 100,000 children less than 5 years of age.
Figure 2
Figure 2
Age distribution of Kawasaki disease patients in Northern European countries (A) and compared to Japan (B).
Figure 2
Figure 2
Age distribution of Kawasaki disease patients in Northern European countries (A) and compared to Japan (B).

References

    1. Nakamura Y, Yashiro M, Uehara R, et al. Epidemiologic features of Kawasaki disease in Japan: results of the 2007–2008 nationwide survey. J Epidemiol. 2010;20(4):302–307. - PMC - PubMed
    1. Harnden A, Alves B, Sheikh A. Rising incidence of Kawasaki disease in England: analysis of hospital admission data. Bmj. 2002 Jun 15;324(7351):1424–1425. - PMC - PubMed
    1. Fischer TK, Holman RC, Yorita KL, Belay ED, Melbye M, Koch A. Kawasaki syndrome in Denmark. Pediatr Infect Dis J. 2007 May;26(5):411–415. - PubMed
    1. Burns JC, Shimizu C, Gonzalez E, et al. Genetic Variations in the Receptor-Ligand Pair CCR5 and CCL3L1 Are Important Determinants of Susceptibility to Kawasaki Disease. J Infect Dis. 2005 Jul 15;192(2):344–349. - PMC - PubMed

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