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Comment
. 2012 Jun 22;149(7):1422-3.
doi: 10.1016/j.cell.2012.06.008.

Rewriting the epigenome

Benjamin R Carone  1 , Oliver J Rando
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Free article
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Rewriting the epigenome

Benjamin R Carone et al. Cell. .
Free article

Abstract

The eukaryotic genome is packaged into a highly ordered chromatin structure, with specific domains regulating the transcription patterns of local genes. Hathaway et al. now present a breakthrough technique in the artificial induction of chromatin marks and use this experimental model to test the properties of an induced heterochromatic domain.

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