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Case Reports
. 2012 Jan;19(1):77-8.
doi: 10.4103/0971-6580.94503.

Super vasomol hair dye poisoning

Affiliations
Case Reports

Super vasomol hair dye poisoning

Praveen A S Kumar et al. Toxicol Int. 2012 Jan.

Abstract

Hair dye poisoning is not rare but is an emerging poisoning in India. The main component of hair dye causing toxicity is paraphenylenediamine (PPD). Acute poisoning by PPD causes characteristic severe angioedema of the upper airway accompanied by a swollen, dry, hard, and protruding tongue. Systemic intoxication results in multisystem involvement and can cause rhabdomyolysis, acute renal failure (ARF). PPD consumption is an uncommon cause of ARF. There is no specific antidote for PPD and treatment is mainly supportive. We report a case of suicidal ingestion of hair dye that presented with cervicofascial edema and later developed rhabdomyolysis and ARF. Our patient improved with dialysis and symptomatic management.

Keywords: Acute renal failure; hair dye; paraphenylenediamine; rhabdomyolysis.

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Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Bhargava P, Matthew P. Hair dye poisoning. J Assoc Physicians India. 2007;55:871–2. - PubMed
    1. Huerta-Alardin AL, Varon J, Marik PE. Bench-to-bedside review: Rhabdomyolysis – An overview for clinicians. Crit Care. 2005;9:158–69. - PMC - PubMed
    1. Filali A, Semlali I, Ottaviano V, Furnari C, Corradini D, Soulaymani R. A retrospective study of acute systemic poisoning of paraphenylenediamine (occidental takawt in Morocco) Afr J Tradit Complement Altern Med. 2006;39:142–9.
    1. El-Ansary EH, Ahmed ME, Clague HW. Systemic toxicity of paraphenylene diamine. Lancet. 1983;1:1341. - PubMed
    1. Hamdouk M. PPD Nephrotoxicity: [Sheffield] Sheffield Kidney Institute; 2001. Paraphenylenediamine (Hair Dye) Acute Systemic toxicity; pp. 34–47.

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