CD8(+) T lymphocytes infiltrating breast cancer: A promising new prognostic marker?
- PMID: 22737616
- PMCID: PMC3382867
- DOI: 10.4161/onci.18614
CD8(+) T lymphocytes infiltrating breast cancer: A promising new prognostic marker?
Abstract
Lymphocytic infiltration is often seen in breast cancer and has been suggested as a marker of host anti-tumor response but its importance in prognosis remains controversial. Our recent study demonstrated an association between tumor-infiltrating CD8(+) T lymphocytes in invasive breast cancer and better prognosis.
Figures
References
-
- Sato E, Olson SH, Ahn J, Bundy B, Nishikawa H, Qian F, et al. Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer. Proc Natl Acad Sci USA. 2005;102:18538–43. doi: 10.1073/pnas.0509182102. - DOI - PMC - PubMed
-
- Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC cancer staging handbook (Springer, New York, 2010).
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials