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. 2012 Feb;3(2):343-345.
doi: 10.3892/ol.2011.476. Epub 2011 Nov 10.

Transitional cell carcinoma of the urinary bladder metastatic to the oral mucosa

Kyu Seob Lee  1 , Ik Chan Song, Hwan Jung Yun, Deog Yeon Jo, Samyong Kim, Hyo Jin Lee
Affiliations

Transitional cell carcinoma of the urinary bladder metastatic to the oral mucosa

Kyu Seob Lee et al. Oncol Lett. 2012 Feb.

Abstract

Metastatic tumors in the oral cavity are rare and usually affect the jaws more often than the oral soft tissues. In particular, metastases confined to the oral mucosa are extremely rare and originate mainly from the lung and breast. Only one case restricted to the oral mucosa and originating from urinary bladder carcinoma has previously been described. We report on a painful polypoid mass located in the oral mucosa with no bone involvement that was confirmed to be a metastatic oral tumor that originated from transitional cell carcinoma of the urinary bladder and progressed rapidly.

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Figures

Figure 1
Figure 1
Microscopic examination of the cystectomy specimen reveals papillary transitional cell carcinoma in the bladder epithelium infiltrating the lamina propria (hematoxylin and eosin; original magnification, ×100).
Figure 2
Figure 2
Gross appearance of the metastatic tumor located in the vestibule of the mouth. The polypoid mass reveals an irregular, somewhat lobulated surface with yellowish exudates.
Figure 3
Figure 3
Biopsy specimen of the polypoid mass reveals papillary transitional cell carcinoma (hematoxylin and eosin; original magnification, ×200).
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