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. 2012 Mar;3(3):646-648.
doi: 10.3892/ol.2011.524. Epub 2011 Dec 14.

A case of pulmonary sclerosing hemangioma with low (18)FDG uptake in PET

Qingyong Chen  1 , Li Jun Wu, Huizhen Hu, Jia Song, Yuquan Wu, Jie Yan, Jianguo Shi
Affiliations

A case of pulmonary sclerosing hemangioma with low (18)FDG uptake in PET

Qingyong Chen et al. Oncol Lett. 2012 Mar.

Abstract

Pulmonary sclerosing hemangioma (PSH) is a relatively rare benign neoplasm, often asymptomatic and presenting as a solitary pulmonary nodule on radiological imaging studies. In the present case report, we examined a case of PSH in a young adult female, and reviewed the literature pertaining to PSH with an emphasis on (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)FDG PET/CT) and pathology. Immunohistochemical staining was also performed to confirm the diagnosis of sclerosing hemangioma. The results revealed that the tumor cells were immunopositive for epithelial membrane antigen, thyroid transcription factor-1 and vimentin and cytoskeleton 7. The patient recovered and was discharged. Thus, (18)FDG PET/CT may be used in the diagnosis of a solitary benign pulmonary nodule.

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Figures

Figure 1
Figure 1
Chest computed tomography (CT) on admission shows a mass with an irregular margin, and which is slightly lobulated in the right lower lobe.
Figure 2
Figure 2
Contrast-enhanced CT image of the thorax with mediastinal windows showing the clearly lobulated mass as a hypervascular lesion. CT, computed tomography.
Figure 3
Figure 3
FDG-PET/CT imaging shows a well-defined nodule with low FDG uptake. FDG-PET/CT, F-fluorodeoxyglucose positron emission tomography/computed tomography.
Figure 4
Figure 4
Microscopic histopathological image of the sclerosing hemangioma shows typical histological patterns that characterize sclerosing hemangioma of the lung.
See this image and copyright information in PMC

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