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. 2012:2012:480715.
doi: 10.1155/2012/480715. Epub 2012 Apr 18.

Traditional Chinese Medicine ZHENG Identification Provides a Novel Stratification Approach in Patients with Allergic Rhinitis

Kai-Li Liang  1 , Rong-San Jiang, Chia-Lin Lee, Pei-Jung Chiang, Jui-Shan Lin, Yi-Chang Su
Affiliations

Traditional Chinese Medicine ZHENG Identification Provides a Novel Stratification Approach in Patients with Allergic Rhinitis

Kai-Li Liang et al. Evid Based Complement Alternat Med. 2012.

Abstract

Background. We aimed to apply the ZHENG identification to provide an easy and useful tool to stratify the patients with allergic rhinitis (AR) through exploring the correlation between the quantified scores of AR symptoms and the TCM ZHENGs. Methods. A total of 114 AR patients were enrolled in this observational study. All participants received the examinations of anterior rhinoscopy and acoustic rhinometry. Their blood samples were collected for measurement of total serum immunoglobulin E (IgE), blood eosinophil count (Eos), and serum eosinophil cationic protein (ECP). They also received two questionnaire to assess the severity scores of AR symptoms and quantified TCM ZHENG scores. Multiple linear regression analysis was used to determine explanatory factors for the score of AR manifestations. Results. IgE and ECP level, duration of AR, the 2 derived TCMZHENG scores of "Yin-Xu - Yang-Xu", and "Qi-Xu + Blood-Xu" were 5 explanatory variables to predict the severity scores of AR symptoms. The patients who had higher scores of "Yin-Xu - Yang-Xu" or "Qi-Xu + Blood-Xu" tended to manifest as "sneezer and runner" or "blockers," respectively. Conclusions. The TCM ZHENG scores correlated with the severity scores of AR symptoms and provided an easy and useful tool to stratify the AR patients.

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Figures

Figure 1
Figure 1
Illustration of the TCM ZHENGs and their derivative parameter. (a) Level of Yang, Yin, Qi, and Blood in normal physiological functional status. (b) Level of Yang, Yin, Qi, and Blood in pathological functional status.
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