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. 2012 Dec;25(12):2789-92.
doi: 10.3109/14767058.2012.705395. Epub 2012 Jul 19.

Abnormal spiral arteries modification in stillbirths: the role of maternal prepregnancy body mass index

Laura Avagliano  1 , Anna Maria Marconi, Solange Romagnoli, Gaetano Pietro Bulfamante
Affiliations

Abnormal spiral arteries modification in stillbirths: the role of maternal prepregnancy body mass index

Laura Avagliano et al. J Matern Fetal Neonatal Med. 2012 Dec.

Abstract

Aim: To evaluate the prevalence of abnormal spiral arteries modification (ASAM) in stillbirths and its anatomo-clinical correlations.

Methods: Two-hundred and three placentas of stillbirth ≥20 weeks of gestation were analyzed.

Results: ASAM was present in 69/203 cases (33.9%). The only maternal characteristic that significantly differed in ASAM versus normal spiral arteries modification (NSAM) cases was the prepregnancy body mass index (BMI) (25.9 ± 6.1 and 23.1 ± 4.2 kg/m(2), respectively) with 15.9% of obesity in ASAM mothers versus 5.2% in NSAM (p = 0.02).

Conclusion: Given the association between obesity and adverse pregnancy outcome, our data suggest that counselling obese women to lose weight before pregnancy becomes increasingly imperative.

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