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. 2012 Jun 29;13(6):246.
doi: 10.1186/gb-2012-13-6-246.

The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities

The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities

Jane W Y Ng et al. Genome Biol. .

Abstract

Longitudinal cohort studies are ideal for investigating how epigenetic patterns change over time and relate to changing exposure patterns and the development of disease. We highlight the challenges and opportunities in this approach.

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References

    1. Relton CL, Davey Smith G. Is epidemiology ready for epigenetics?. Int J Epidemiol. 2012;41:5–9. doi: 10.1093/ije/dys006. - DOI - PMC - PubMed
    1. Davey Smith G. Epigenetics for the masses: more than Audrey Hepburn and yellow mice?. Int J Epidemiol. 2012;41:303–308. doi: 10.1093/ije/dys030. - DOI
    1. Maher B. Personal genomes: The case of the missing heritability. Nature. 2008;456:18–21. - PubMed
    1. Michels KB. The promises and challenges of epigenetic epidemiology. Exp Gerontol. 2010;45:297–301. doi: 10.1016/j.exger.2009.12.011. - DOI - PubMed
    1. Relton CL, Davey Smith G. Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment. PLoS Med. 2010;7:e1000356. doi: 10.1371/journal.pmed.1000356. - DOI - PMC - PubMed

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