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Comment
. 2012 Jun 29;36(6):899-901.
doi: 10.1016/j.immuni.2012.06.002.

SAP signaling: a dual mechanism of action

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SAP signaling: a dual mechanism of action

Marie Le Borgne et al. Immunity. .
Free article

Abstract

In this issue of Immunity, Kageyama et al. (2012), Zhao et al. (2012), and Dong et al. (2012) show that the adaptor protein SAP regulates both positive and negative signals through SLAM receptors to stabilize intercellular contacts.

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