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Comment
. 2012 Jun 29;36(6):901-3.
doi: 10.1016/j.immuni.2012.06.001.

Bystanders not so innocent after all

Marcel Batten  1 , Nico Ghilardi
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Free article
Comment

Bystanders not so innocent after all

Marcel Batten et al. Immunity. .
Free article

Abstract

Interleukin 27 (IL-27) regulates immune responses, including T helper 17 (Th17) cell activity. In this issue of Immunity, Hirahara et al. (2012) demonstrate that IL-27 suppresses Th17 cells in trans through induction of the inhibitory ligand PD-L1 on bystander T cells.

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