Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977;42(3-4):175-89.

Heavy particle therapy: pituitary tumors

J A Linfoot, J S Nakagawa, E Wiedemann, J Lyman, C Chong, J Garcia, J H Lawrence
  • PMID: 227502

Heavy particle therapy: pituitary tumors

J A Linfoot et al. Bull Los Angeles Neurol Soc. 1977.

Abstract

Therapy with 910 MeV alpha particles provides a treatment with no mortality and an extremely low morbidity and has been highly successful in the control of pituitary hormone hypersecretion and tumor growth. It is possible to deliver radiation doses to the pituitary gland that are sufficiently high to inhibit or destroy the tumor cells that cause abnormal secretory activity without damaging the surrounding structures. The data demonstrate the effectiveness of this form of treatment in acromegaly, non-functioning pituitary tumors, prolactin secreting adenomas, Cushing's disease and Nelson's syndrome.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

  • Treatment of acromegaly.
    Thomas JP. Thomas JP. Br Med J (Clin Res Ed). 1983 Jan 29;286(6362):330-2. doi: 10.1136/bmj.286.6362.330. Br Med J (Clin Res Ed). 1983. PMID: 6402086 Free PMC article. Review. No abstract available.
  • Corticotroph tumor progression after bilateral adrenalectomy (Nelson's syndrome): systematic review and expert consensus recommendations.
    Reincke M, Albani A, Assie G, Bancos I, Brue T, Buchfelder M, Chabre O, Ceccato F, Daniele A, Detomas M, Di Dalmazi G, Elenkova A, Findling J, Grossman AB, Gomez-Sanchez CE, Heaney AP, Honegger J, Karavitaki N, Lacroix A, Laws ER, Losa M, Murakami M, Newell-Price J, Pecori Giraldi F, Pérez-Rivas LG, Pivonello R, Rainey WE, Sbiera S, Schopohl J, Stratakis CA, Theodoropoulou M, van Rossum EFC, Valassi E, Zacharieva S, Rubinstein G, Ritzel K. Reincke M, et al. Eur J Endocrinol. 2021 Mar;184(3):P1-P16. doi: 10.1530/EJE-20-1088. Eur J Endocrinol. 2021. PMID: 33444221 Free PMC article.