Colorectal cancer: A step closer to combating acquired resistance in CRC

Comment

Lisa Hutchinson. Nat Rev Gastroenterol Hepatol. 2012 Aug.

. 2012 Aug;9(8):427.

doi: 10.1038/nrgastro.2012.128. Epub 2012 Jul 3.

No abstract available

Comment on

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
Misale S, Yaeger R, Hobor S, Scala E, Janakiraman M, Liska D, Valtorta E, Schiavo R, Buscarino M, Siravegna G, Bencardino K, Cercek A, Chen CT, Veronese S, Zanon C, Sartore-Bianchi A, Gambacorta M, Gallicchio M, Vakiani E, Boscaro V, Medico E, Weiser M, Siena S, Di Nicolantonio F, Solit D, Bardelli A. Misale S, et al. Nature. 2012 Jun 28;486(7404):532-6. doi: 10.1038/nature11156. Nature. 2012. PMID: 22722830 Free PMC article.
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers.
Diaz LA Jr, Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, Allen B, Bozic I, Reiter JG, Nowak MA, Kinzler KW, Oliner KS, Vogelstein B. Diaz LA Jr, et al. Nature. 2012 Jun 28;486(7404):537-40. doi: 10.1038/nature11219. Nature. 2012. PMID: 22722843 Free PMC article.