Hyponatraemia associated with cardiac tamponade and chronic fluid excess
- PMID: 22752560
- PMCID: PMC3034210
- DOI: 10.1136/bcr.07.2009.2113
Hyponatraemia associated with cardiac tamponade and chronic fluid excess
Abstract
We describe a complex case of hyponatraemia with two aetiologies. A 49-year-old man who drank 6 litres of dilute alcohol per day presented confused and oedematous with a serum sodium of 95 mmol/litre. Urine sodium was <10 mmol/litre and urine osmolality 440 mOsmol/kg. Chest x-ray demonstrated a globular heart. ECG showed saddle-shaped ST elevation. ECHO demonstrated a large pericardial effusion causing marked tamponade. Following pericardiocentesis there was a marked diuresis; serum sodium returned to normal after 2 weeks. A full recovery ensued. Cardiac tamponade is associated with antidiuresis via release of antidiuretic hormone (ADH). Tamponade is also associated with antinatriuresis. Antidiuresis and antinatriuresis usually balance in cardiac tamponade; excessive fluid intake may have caused an imbalance in this case.
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References
-
- Raff H, Cogswell T, Bernath G, et al. Vasopressin and ACTH responses to acute cardiac tamponade in conscious dogs. Clin Res 1986;34:899
-
- Mancini GB, McGillem MJ, Bates ER, et al. Hormonal responses to cardiac tamponade: inhibition of release of atrial natriuretic factor despite elevation of atrial pressures. Circulation 1987;76:884–90 - PubMed
-
- Baylis P. Osmoregulation and control of vasopressin secretion in healthy humans. Am J Physiol 1987;253:671–8 - PubMed
-
- Shafique R, Sarwar S, Wall BM, et al. Reversible hyponatremia related to pericardial tamponade. Am J Kidney Dis 2007;50:336–41 - PubMed
-
- Panayiotou H, Haitas B, Hollister AS. Atrial wall tension changes and the release of atrial natriuretic factor on relief of cardiac tamponade. Am Heart J 1995;129:960–7 - PubMed
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