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. 2013 Jul;34(26):1958-63.
doi: 10.1093/eurheartj/ehs172. Epub 2012 Jul 2.

The International Serious Adverse Events Consortium (iSAEC) phenotype standardization project for drug-induced torsades de pointes

Elijah R Behr  1 , Craig January, Eric Schulze-Bahr, Andrew A Grace, Stefan Kääb, Monica Fiszman, Shaniece Gathers, Shaavhrée Buckman, Ashraf Youssef, Munir Pirmohamed, Dan Roden
Affiliations

The International Serious Adverse Events Consortium (iSAEC) phenotype standardization project for drug-induced torsades de pointes

Elijah R Behr et al. Eur Heart J. 2013 Jul.
No abstract available

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Figures

Figure 1
Figure 1
Surface ECGs of polymorphic ventricular tachycardia and TdP. (A) A very short interval between the sinus beat and the subsequent ventricular ectopic (short coupling interval; arrows) and no QT-interval prolongation in the setting of an acute coronary syndrome (note elevated ST segment on the top lead). This is not TdP. (B) An apparent polymorphic tachycardia that is a recording artefact, identified by the continued regular rhythm ‘marching through’ the recording (arrows). (C) A case of TdP with ‘short-long-short’ cycle length changes at initiation, a long QT on the last sinus beat (star), and a long coupling interval.
Figure 2
Figure 2
Algorithm to identify cases of drug-induced torsades de pointes.
See this image and copyright information in PMC

References

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