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Case Reports
. 2010 Jul 7:2010:bcr0220102712.
doi: 10.1136/bcr.02.2010.2712.

Primary pulmonary choriocarcinoma in a male

Akberet Hadgu  1 , Arshdeep Tindni, Mukta Panda
Affiliations
Case Reports

Primary pulmonary choriocarcinoma in a male

Akberet Hadgu et al. BMJ Case Rep. .

Abstract

The authors report a case of a 48-year-old male smoker who presented with respiratory distress and constitutional symptoms along with gynaecomastia and multiple pulmonary nodules. Based on normal physical and ultrasound findings of the testes, presence of markedly elevated serum β human chorionic gonadotrophin (HCG) and biopsy findings of the lung a diagnosis of primary pulmonary choriocarcinoma was made.

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Conflict of interest statement

Competing interests None.

Figures

Figure 1
Figure 1
Chest x-ray showing bilateral pulmonary nodules.
Figure 2
Figure 2
Normal ultrasound of testis.
Figure 3
Figure 3
CT chest (before chemotherapy) showing extensive lymphadenopathy in the mediastinum with extensive and multiple bilateral pulmonary nodules.
Figure 4
Figure 4
CT abdomen showing multiple low density filling defects in the liver.
Figure 5
Figure 5
MRI brain showing metastatic lesion in the left thalamus and right sub cortical matter.
Figure 6
Figure 6
CT guided biopsy of left lung lesion showing syncytiotrophoblastic and cytotrophoblastic-like cells with immunohistochemical results consistent with choriocarcinoma.
Figure 7
Figure 7
CT chest (after chemotherapy) some resolution of the tumour burden.
See this image and copyright information in PMC

References

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    1. Fine G, Smith RW, Jr, Pachter MR. Primary extragenital choriocarcinoma in the male subject. Case report and review of the literature. Am J Med 1962;32:776–94 - PubMed
    1. Ikura Y, Inoue T, Tsukuda H, et al. Primary choriocarcinoma and human chorionic gonadotrophin-producing giant cell carcinoma of the lung: are they independent entities? Histopathology 2000;36:17–25 - PubMed
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