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. 2011 Jul;63(3):260-3.
doi: 10.1007/s12070-011-0165-2. Epub 2011 Apr 13.

Myeloperoxydase expression in the pathogenesis of nasal polyps

Burcin A Sarisoy, Mehmet Eken, Alev Z Oktay, Mustafa Paksoy, Arif Sanli

Myeloperoxydase expression in the pathogenesis of nasal polyps

Burcin A Sarisoy et al. Indian J Otolaryngol Head Neck Surg. 2011 Jul.

Abstract

Nasal polyps are benign mucosal protrusions that expand into the nasal cavity. There are no any etiological factors that may explain the pathogenesis of nasal polyps but currently inflammation continues to be the major factor. As a result of inflammation, neutrophils become activated and migrate to the inflammatory area and form their bactericidal effects by producing free oxygen radicals. The objective of our study is to investigate the expression of myeloperoxydase enzyme, which is usually an indicator of leukocyte infiltration and is responsible in the formation of free oxygen radicals in polyp tissues and to determine its role in the pathogenesis of nasal polyps.

Keywords: Free oxygen radicals; Inflammation; Myeloperoxidase; Nasal polyps.

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Figures

Fig. 1
Fig. 1
Distribution of epithelial cell stained with MPO in all tissues
Fig. 2
Fig. 2
Distrubution of inflammatory cells stained with MPO in all tissues
Fig. 3
Fig. 3
Distribution of epithelial cells stained with MPO between groups
Fig 4
Fig 4
Distrubution of inflammatory cells stained with MPO between groups
See this image and copyright information in PMC

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