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Case Reports
. 2012 Sep;50(9):3129-32.
doi: 10.1128/JCM.00948-12. Epub 2012 Jul 3.

Catheter-related bacteremia caused by multidrug-resistant Leclercia adecarboxylata in a patient with breast cancer

Gee-Wook Shin  1 , Myung-Jo You, Hye-Soo Lee, Chang-Seop Lee
Affiliations
Case Reports

Catheter-related bacteremia caused by multidrug-resistant Leclercia adecarboxylata in a patient with breast cancer

Gee-Wook Shin et al. J Clin Microbiol. 2012 Sep.

Abstract

We report a multidrug-resistant strain of Leclercia adecarboxylata responsible for catheter-related bacteremia in a 47-year-old female with breast cancer. The isolated strain was resistant to several β-lactams, aminoglycosides, and folate pathway inhibitors and harbored bla(TEM-1) and bla(CTX-M) group 1 and intl1 genes (dfrA12-orfF-aadA2) as genetic determinants for resistance. Based on a review of the L. adecarboxylata literature, there have been only 4 reports of antibiotic-resistant strains. To our knowledge, this is the first report of an L. adecarboxylata strain with simultaneous resistance to β-lactams, aminoglycosides, and sulfonamides.

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References

    1. CLSI 2009. Clinical and Laboratory Standards Institute (CLSI) performance standards for antimicrobial disk diffusion susceptibility tests, 19th ed Approved standard, CLSI document M100-S19, vol 29 CLSI, Wayne, PA
    1. Dalamaga M, Pantelaki M, Karmaniolas K, Daskalopoulou K, Migdalis I. 2009. Isolation of Leclercia adecarboxylata from blood and burn wound after a hydrofluoric acid chemical injury. Burns 35:443–445 - PubMed
    1. Dallenne C, Da Costa A, Decre D, Favier C, Arlet G. 2010. Development of a set of multiplex PCR assays for the detection of genes encoding important beta-lactamases in Enterobacteriaceae. J. Antimicrob. Chemother. 65:490–495 - PubMed
    1. de Baere T, et al. 2001. Isolations of Leclercia adecarboxylata from a patient with a chronically inflamed gallbladder and from a patient with sepsis without focus. J. Clin. Microbiol. 39:1674–1675 - PMC - PubMed
    1. De la Obra P, Domingo D, Casaseca R, Del Rey MC, Lopez-Brea M. 1999. Bacteremia due to Leclercia adecarboxylata in a patient with multiple myeloma. Clin. Microbiol. Newsletter 21:142–143

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