Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2012 Sep;50(9):3129-32.
doi: 10.1128/JCM.00948-12. Epub 2012 Jul 3.

Catheter-related bacteremia caused by multidrug-resistant Leclercia adecarboxylata in a patient with breast cancer

Gee-Wook Shin  1 , Myung-Jo You, Hye-Soo Lee, Chang-Seop Lee
Affiliations
Case Reports

Catheter-related bacteremia caused by multidrug-resistant Leclercia adecarboxylata in a patient with breast cancer

Gee-Wook Shin et al. J Clin Microbiol. 2012 Sep.

Abstract

We report a multidrug-resistant strain of Leclercia adecarboxylata responsible for catheter-related bacteremia in a 47-year-old female with breast cancer. The isolated strain was resistant to several β-lactams, aminoglycosides, and folate pathway inhibitors and harbored bla(TEM-1) and bla(CTX-M) group 1 and intl1 genes (dfrA12-orfF-aadA2) as genetic determinants for resistance. Based on a review of the L. adecarboxylata literature, there have been only 4 reports of antibiotic-resistant strains. To our knowledge, this is the first report of an L. adecarboxylata strain with simultaneous resistance to β-lactams, aminoglycosides, and sulfonamides.

PubMed Disclaimer

References

    1. CLSI 2009. Clinical and Laboratory Standards Institute (CLSI) performance standards for antimicrobial disk diffusion susceptibility tests, 19th ed Approved standard, CLSI document M100-S19, vol 29 CLSI, Wayne, PA
    1. Dalamaga M, Pantelaki M, Karmaniolas K, Daskalopoulou K, Migdalis I. 2009. Isolation of Leclercia adecarboxylata from blood and burn wound after a hydrofluoric acid chemical injury. Burns 35:443–445 - PubMed
    1. Dallenne C, Da Costa A, Decre D, Favier C, Arlet G. 2010. Development of a set of multiplex PCR assays for the detection of genes encoding important beta-lactamases in Enterobacteriaceae. J. Antimicrob. Chemother. 65:490–495 - PubMed
    1. de Baere T, et al. 2001. Isolations of Leclercia adecarboxylata from a patient with a chronically inflamed gallbladder and from a patient with sepsis without focus. J. Clin. Microbiol. 39:1674–1675 - PMC - PubMed
    1. De la Obra P, Domingo D, Casaseca R, Del Rey MC, Lopez-Brea M. 1999. Bacteremia due to Leclercia adecarboxylata in a patient with multiple myeloma. Clin. Microbiol. Newsletter 21:142–143

Publication types

MeSH terms

Associated data

LinkOut - more resources