Ebola and Marburg hemorrhagic fevers: neglected tropical diseases?
- PMID: 22761967
- PMCID: PMC3385614
- DOI: 10.1371/journal.pntd.0001546
Ebola and Marburg hemorrhagic fevers: neglected tropical diseases?
Abstract
Ebola hemorrhagic fever (EHF) and Marburg hemorrhagic fever (MHF) are rare viral diseases, endemic to central Africa. The overall burden of EHF and MHF is small in comparison to the more common protozoan, helminth, and bacterial diseases typically referred to as neglected tropical diseases (NTDs). However, EHF and MHF outbreaks typically occur in resource-limited settings, and many aspects of these outbreaks are a direct consequence of impoverished conditions. We will discuss aspects of EHF and MHF disease, in comparison to the "classic" NTDs, and examine potential ways forward in the prevention and control of EHF and MHF in sub-Saharan Africa, as well as examine the potential for application of novel vaccines or antiviral drugs for prevention or control of EHF and MHF among populations at highest risk for disease.
Conflict of interest statement
The authors have declared that no competing interests exist.
Figures
References
-
- Sanchez A, Geisbert TW, Feldmann H. Knipe DM, Howley PM, editors. Filoviridae: Marburg and Ebola viruses. 2007. Fields Virology: Lippincott Williams&Wilkins.
-
- Semmler IA. Ebola goes pop: the filovirus from literature into film. Lit Med. 1998;17:149–174. - PubMed
-
- Leroy EM, Gonzalez JP, Baize S. Ebola and Marburg haemorrhagic fever viruses: major scientific advances, but a relatively minor public health threat for Africa. Clin Microbiol Infect. 2011;17:964–976. - PubMed
-
- Borio L, Inglesby T, Peters CJ, Schmaljohn AL, Hughes JM, et al. Hemorrhagic fever viruses as biological weapons: medical and public health management. JAMA. 2002;287:2391–2405. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
