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Randomized Controlled Trial
. 2011;26(3):22-4.

[Lidocaine in endotracheal intubation]

[Article in French]
B M Samaké  1 , O Goita, D Goita, A Diallo, Y Coulibaly
Affiliations
  • PMID: 22766210
Randomized Controlled Trial

[Lidocaine in endotracheal intubation]

[Article in French]
B M Samaké et al. Mali Med. 2011.

Abstract

Aim: To evaluate the effect of lidocaîne use by IV during endotracheal intubation.

Patients and method: Our study was simple insu randomized prospective and comparative. It was done at the teaching hospital Gabriel Touré of Bamako from march to September 2005. Patients were distributed in 3 groups. The first group I: got fentanyl 2 nmg /kg+penthotal 5mg/kg+vecuronium 0.1mg/kg and intubation 3 mn later. The group II: lodocaîne 1,5mg +fentanyl 2nmg/kg+penthotal 5mg /kg + vecuronium 0.1mg/kg and intubation 3mn later. The group III: lodocaïne 1.5 mg/kg+pentothal 5mg/kg+vecuronium 0.1mg/kg and intubation 3 mn later.

Results: The mean arterial pression to intubation has been 105.88±13.82 mmhg in the groupI, 96.60±15.01mmhg in the group II and 96.44±12.09mmhg in the group III with P = 0.008. To incision it has been 99.12±11.82 in the group I, 94.90 ±6.67 mmhg in the group II and 92.26±8.81 mmhg in the groupIII with P = 0.017.

Conclusion: Lidocaïne, used alone in Iv or associated to fentanyl 3 mn before intubation prevents hypertension related to intubation and incision.

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