Evaluation of BACTEC MGIT 960 system for the second-line drugs susceptibility testing of Mycobacterium tuberculosis in China
- PMID: 22766324
- DOI: 10.1016/j.mimet.2012.06.010
Evaluation of BACTEC MGIT 960 system for the second-line drugs susceptibility testing of Mycobacterium tuberculosis in China
Abstract
When the performance of the BACTEC MGIT 960 system was evaluated with the traditional proportion method (PM) on 321 clinical isolates of Mycobacterium tuberculosis from China, concordance values were 98.44% capreomycin, 98.75% kanamycin, 98.75% ofloxacin and 94.08% ethionamide. The turnaround time with BACTEC MGIT 960 system (7.5±1.8 days) was significantly shorter than with PM (28 days or 42 days). Therefore, the BACTEC MGIT 960 system was a reliable and rapid method for second-line drug susceptibility testing of TB in China.
Copyright © 2012. Published by Elsevier B.V.
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