Interaction of ethanol, cholesterol and vitamin A on phospholipid methylation in hepatic microsomes of rats
Affiliations
- PMID: 2276880
Item in Clipboard
Interaction of ethanol, cholesterol and vitamin A on phospholipid methylation in hepatic microsomes of rats
Int J Vitam Nutr Res.
1990.
Abstract
Effect of ethanol, cholesterol and vitamin A either alone or in combination has been studied on cyt P450 and phospholipid methylation in hepatic microsomes of rats. Ethanol increased cyt P450 activity and decreased phospholipid methylation. Cholesterol effects were opposite to ethanol. Combination of cholesterol and ethanol decreased cyt P450 activity and increased phospholipid methylation. Vitamin A, which alone did not affect cyt P450 activity and phospholipid methylation behaved like cholesterol when given along with ethanol.
Similar articles
-
Interactions of phospholipase D and cytochrome P450 protein stability.Biochem Pharmacol. 2004 Aug 1;68(3):503-12. doi: 10.1016/j.bcp.2004.04.004. Biochem Pharmacol. 2004. PMID: 15242816
-
Effect of simulated hypoxia (7620 m, 6 h) on hepatic microsomal drug metabolising enzymes activity in rats given ethanol and vitamin A.Int J Vitam Nutr Res. 1987;57(2):115-9. Int J Vitam Nutr Res. 1987. PMID: 3654102
-
Alterations induced by chronic ethanol treatment on lipid composition of microsomes, mitochondria and myelin from neonatal chick liver and brain.Biochem Int. 1986 Jan;12(1):51-60. Biochem Int. 1986. PMID: 3947374
-
Effect of swimming exercise and ethanol on rat liver P450-dependent monooxygenases.Med Sci Sports Exerc. 1994 Dec;26(12):1453-8. Med Sci Sports Exerc. 1994. PMID: 7869878
-
Effect of beta-carotene on hepatic cytochrome P-450 in ethanol-fed rats.Alcohol Clin Exp Res. 2001 Sep;25(9):1368-72. Alcohol Clin Exp Res. 2001. PMID: 11584158
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical