Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2012 Jul 3;16(1):6-8.
doi: 10.1016/j.cmet.2012.06.010.

Caloric restriction in mTORC1 control of intestinal homeostasis

Thurl E Harris, Michael O Thorner
Free article
Comment

Caloric restriction in mTORC1 control of intestinal homeostasis

Thurl E Harris et al. Cell Metab. .
Free article

Abstract

Reducing caloric intake, while maintaining adequate nutrition, promotes longevity in diverse organisms, possibly by preserving stem and progenitor cell function. Yilmaz and colleagues (2012) now show that caloric restriction alters intestinal stem cell proliferation and differentiation, and elucidate a mechanism for how the mammalian stem cell niche responds to environmental inputs.

PubMed Disclaimer

Comment on

LinkOut - more resources