The use of human acellular dermal matrix in the prevention of infra-auricular depressed deformities and Frey's syndrome following total parotidectomy

Abstract

Background: The aim of the study was to explore whether human acellular dermal matrix (ADM) implantation could prevent infra-auricular depressed deformities and Frey's syndrome following total parotidectomy.

Methods: We analyzed 41 cases of total parotidectomy (control group) and 29 cases of simultaneous ADM implantation following total parotidectomy (ADM group) for infra-auricular depressed deformities and the presence of gustatory flushing or sweating. The follow-up periods ranged from 6 months to 7 years.

Results: Facial contours and bilateral symmetry improved after surgery in the ADM group. In the control group, an infra-auricular depressed deformity was evident in all 41 cases. Frey's syndrome was recorded in 1 patient (3.4%) from the ADM group and 14 patients (34.1%) from the control group. No cases of immune rejection, infection, hematoma, or salivary fistula were observed in either group.

Conclusions: The use of ADM could reduce postoperative facial contour deformities and Frey's syndrome following total parotidectomy.