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. 2012 Oct;106(10):629-31.
doi: 10.1016/j.trstmh.2012.05.007. Epub 2012 Jul 7.

Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand

Rapeephan R Maude  1 , Teerapon Vatcharapreechasakul, Pitchayanant Ariyaprasert, Richard J Maude, Maliwan Hongsuwan, Prayoon Yuentrakul, Direk Limmathurotsakul, Gavin C K W Koh, Wipada Chaowagul, Nicholas P J Day, Sharon J Peacock
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Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand

Rapeephan R Maude et al. Trans R Soc Trop Med Hyg. 2012 Oct.

Abstract

Retrospective case series from Thailand have reported the presence of intra-abdominal abscesses in around half of patients with melioidosis, a much higher rate than our clinical experience would suggest. We performed a prospective, observational study of 230 adult patients with culture-confirmed melioidosis in which all patients underwent abdominal ultrasound. One or more abscesses were detected in the liver and/or spleen in 77 (33%) cases. These were often multiple (70%, 31/44 in hepatic abscesses and 88%, 50/57 in splenic abscesses) and clinically silent (27% of cases with abscesses presenting with abdominal pain). The mortality rate at 4 weeks post-discharge was lower in patients who were abscess-positive vs abscess-negative (10%, 8/77 vs 20%, 31/153).

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