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. 2013 Jan 1;127(1-3):243-7.
doi: 10.1016/j.drugalcdep.2012.06.020. Epub 2012 Jul 6.

Prevalence of mood and substance use disorders among patients seeking primary care office-based buprenorphine/naloxone treatment

Jonathan D Savant  1 , Declan T Barry, Christopher J Cutter, Michelle T Joy, An Dinh, Richard S Schottenfeld, David A Fiellin
Affiliations

Prevalence of mood and substance use disorders among patients seeking primary care office-based buprenorphine/naloxone treatment

Jonathan D Savant et al. Drug Alcohol Depend. .

Abstract

Background: Psychiatric comorbidity can adversely affect opioid dependence treatment outcomes. While the prevalence of psychiatric comorbidity among patients seeking methadone maintenance treatment has been documented, the extent to which these findings extend to patients seeking primary care office-based buprenorphine/naloxone treatment is unclear.

Aims: To determine the prevalence of mood and substance use disorders among patients seeking primary care office-based buprenorphine/naloxone treatment, via cross sectional survey.

Methods: 237 consecutive patients seeking primary care office-based buprenorphine/naloxone treatment were evaluated using modules from the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Current (past 30 days) and past diagnoses were cataloged separately.

Results: Patients ranged in age from 18 to 62 years old (M=33.9, SD=9.9); 173 (73%) were men; 197 (83%) were white. Major depression was the most prevalent mood disorder (19% current, 24% past). A minority of patients met criteria for current dysthymia (6%), past mania (1%), or past hypomania (2%). While 37 patients (16%) met criteria for current abuse of or dependence on at least one non-opioid substance (7% cocaine, 4% alcohol, 4% cannabis, 2% sedatives, 0.4% stimulants, 0.4% polydrug), 168 patients (70%) percent met criteria for past abuse of or dependence on at least one non-opioid substance (43% alcohol, 38% cannabis, 30% cocaine, 9% sedatives, 8% hallucinogens, 4% stimulants, 1% polydrug, and 0.4% other substances).

Conclusion: Mood and substance use comorbidity is prevalent among patients seeking primary care office-based buprenorphine/naloxone treatment. The findings support the need for clinicians to assess and address these conditions.

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Conflict of interest statement

Conflict of Interest

No conflict declared.

References

    1. Alford DP, LaBelle CT, Kretsch N, Bergeron A, Winter M, Botticelli M, Samet JH. Collaborative care of opioid-addicted patients in primary care using buprenorphine: five-year experience. Arch Intern Med. 2011;171:425–431. - PMC - PubMed
    1. Brooner RK, King VL, Kidorf M, Schmidt CW, Jr, Bigelow GE. Psychiatric and substance use comorbidity among treatment-seeking opioid abusers. Arch Gen Psychiatry. 1997;54:71–80. - PubMed
    1. Bux DA, Lamb RJ, Iguchi MY. Cocaine use and HIV risk behavior in methadone maintenance patients. Drug Alcohol Depend. 1995;37:29–35. - PubMed
    1. Cacciola JS, Alterman AI, Rutherford MJ, McKay JR, Mulvaney FD. The relationship of psychiatric comorbidity to treatment outcomes in methadone maintained patients. Drug Alcohol Depend. 2001;61:271–280. - PubMed
    1. Carpentier PJ, Krabbe PFM, Van Gogh MT, Knapen LJM, Buitelaar JK, De Jong CAJ. Psychiatric comorbidity reduces quality of life in chronic methadone maintained patients. Am J Addict. 2009;18:470–480. - PubMed

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