Comparative Study
[Interactions of digoxin with nifedipine and diltiazem]
[Article in
Polish]
Affiliations
- PMID: 2277790
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Comparative Study
[Interactions of digoxin with nifedipine and diltiazem]
[Article in
Polish]
Pol Tyg Lek.
1990 Jun.
Abstract
Biological serum halt-life, relative volume of distribution and digoxin clearance following a single oral dose of digoxin with diltiazem or nifedipine were evaluated. Blood serum digoxin following its administration with diltiazem and nifedipine for 8 days were assayed. It was found that diltiazem and nifedipine did not affect tested pharmacokinetic parameters of digoxin and did not change digoxin serum levels during a 8-day administration in combination with diltiazem and nifedipine.
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