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Review
. 2012:2012:946813.
doi: 10.1155/2012/946813. Epub 2012 Jun 18.

Role of prostaglandins in neuroinflammatory and neurodegenerative diseases

Isabel Vieira de Assis Lima  1 , Leandro Francisco Silva Bastos, Marcelo Limborço-Filho, Bernd L Fiebich, Antonio Carlos Pinheiro de Oliveira
Affiliations
Review

Role of prostaglandins in neuroinflammatory and neurodegenerative diseases

Isabel Vieira de Assis Lima et al. Mediators Inflamm. 2012.

Abstract

Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role. The effects induced by prostaglandins might be mediated by activation of their known receptors or by nonclassical mechanisms. In the present paper, we discuss the evidences that link prostaglandins, as well as the enzymes that produce them, to some neurological diseases.

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