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Review
. 2012 Jul-Aug;13(4):505-9.
doi: 10.3348/kjr.2012.13.4.505. Epub 2012 Jun 18.

Acute severe thrombocytopenia following non-ionic low-osmolarity intravenous contrast medium injection

Pal Bata  1 , Adam Domonkos Tarnoki, David Laszlo Tarnoki, Evelin Horvath, Viktor Berczi, Ferenc Szalay
Affiliations
Review

Acute severe thrombocytopenia following non-ionic low-osmolarity intravenous contrast medium injection

Pal Bata et al. Korean J Radiol. 2012 Jul-Aug.

Abstract

Intravenous contrast medium (ICM) rarely induces anaphylactic reactions, including urticaria, hypotension and respiratory failure. Even the most modern ICM may cause such adverse events. Thrombocytopenia has been reported as an extreme rare consequence of ICM. Here we report on a case of a 72-year-old male patient with a self-limiting severe acute thrombocytopenia following administration of intravenous non-ionic low-osmolarity contrast medium. No such low platelet count has ever been reported. We also present a review of the literature.

Keywords: Immunoallergic mechanism; Intravenous contrast material; Thrombocytopenia.

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Figures

Fig. 1
Fig. 1
Platelet (PLT) level before and after development of acute severe thrombocytopenia. It should be noted that time scale is non-proportional; it refers to Dates studied.
See this image and copyright information in PMC

References

    1. Wiemer M, Kreuzpaintner G, Lauer B, Kiefel V, Schultheiss HP, Horstkotte D, et al. [Recurrent immune thrombocytopenia: a rare complication after contrast medium injection] Dtsch Med Wochenschr. 1995;120:1236–1240. - PubMed
    1. Lacy J, Bober-Sorcinelli KE, Farber LR, Glickman MG. Acute thrombocytopenia induced by parenteral radiographic contrast medium. AJR Am J Roentgenol. 1986;146:1298–1299. - PubMed
    1. Shojania AM. Immune-mediated thrombocytopenia due to an iodinated contrast medium (diatrizoate) Can Med Assoc J. 1985;133:123. - PMC - PubMed
    1. Chang JC, Lee D, Gross HM. Acute thrombocytopenia after i.v. administration of a radiographic contrast medium. AJR Am J Roentgenol. 1989;152:947–949. - PubMed
    1. Wein P, Handler M, Chadda KD. Severe thrombocytopenia as a result of contrast left ventricular angiography. Cathet Cardiovasc Diagn. 1982;8:495–499. - PubMed