Cytohistological correlation of early changes in spontaneously infarcted fibroadenoma-a rare case report

Abstract

Fibroadenoma is the most commonly diagnosed benign tumour in adolescents and young women but spontaneous infarction in fibroadenoma is rarely seen. We report here a case of spontaneously infracted fibroadenoma in a 20 year old unmarried female without history of trauma or previous fine needle aspiration. It is important to recognize this entity because microscopic findings in an infarct are influenced by the duration of the infarct and on cytology it mimics mastitis, duct ectasia and even carcinoma.

Figure 1:. Cellular smears showing tight clusters of duct epithelial cells and myoepithelial cells with abundant ghost epithelial cells (4000 × 3000 pixels)(H & E stain).

Figure 2:. (FNAC SMEAR) Cellular smears showing fibromyxoid stroma in the background of abundant ghost epithelial cells(4000 × 3000 pixels)(H & E stain).

Figure 3:. Hemorrhagic infarct in intracanalicular type of fibroadenoma (4000 × 3000 pixels)(H & E stain).

Figure 4:. Desquamation of lining epithelial cells which appeared as the ghost cells in the cytology smears (4000 x 3000 pixels)(H & E stain).

Figure 5:. Complete disintegration of architecture forming cystic space containing singly scattered stromal and ductal cells (ghost epithelial cells) (4000 × 3000 pixels)(H & E stain).