Anesthetic management of HELLP syndrome complicating primary antiphospholipid syndrome -A case report-
- PMID: 22778897
- PMCID: PMC3384799
- DOI: 10.4097/kjae.2012.62.6.575
Anesthetic management of HELLP syndrome complicating primary antiphospholipid syndrome -A case report-
Abstract
Antiphospholipid syndrome (APS) is defined as an autoimmune disorder characterized by recurrent thrombosis or obstetrical morbidity. A 29-year-old woman who was diagnosed with APS underwent emergency cesarean delivery at 23 weeks' gestation. She had a seizure attack and her laboratory findings were: AST/ALT 1459/1108 IU/L, LDH 1424 IU/L, 30% hematocrit, a platelet count of 43 × 10(3)/ml and urine protein (4+). We describe the anesthetic experience of catastrophic HELLP syndrome with antiphospholipid syndrome and we review the relevant literature.
Keywords: Antiphospholipid syndrome; Eclampsia; HELLP.
Similar articles
-
Hepatic infarction in a pregnant woman with antiphospholipid syndrome and triple antibody positivity: A case report focusing on catastrophic antiphospholipid syndrome.Obstet Gynecol Sci. 2016 Sep;59(5):397-402. doi: 10.5468/ogs.2016.59.5.397. Epub 2016 Sep 13. Obstet Gynecol Sci. 2016. PMID: 27668204 Free PMC article.
-
Thrombotic microangiopathy with liver, gut, and bone infarction (catastrophic antiphospholipid syndrome) associated with HELLP syndrome.Clin Rheumatol. 2005 Apr;24(2):166-8. doi: 10.1007/s10067-004-1017-1. Epub 2004 Dec 8. Clin Rheumatol. 2005. PMID: 15592692
-
HELLP Syndrome at 17 Weeks Gestation: A Rare and Catastrophic Phenomenon.J Clin Gynecol Obstet. 2014 Dec;3(4):147-150. doi: 10.14740/jcgo297w. J Clin Gynecol Obstet. 2014. PMID: 25806101 Free PMC article.
-
Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome.Rheumatol Int. 2007 Dec;28(2):171-4. doi: 10.1007/s00296-007-0386-6. Epub 2007 Jun 19. Rheumatol Int. 2007. PMID: 17576561 Review.
-
The HELLP syndrome: clinical issues and management. A Review.BMC Pregnancy Childbirth. 2009 Feb 26;9:8. doi: 10.1186/1471-2393-9-8. BMC Pregnancy Childbirth. 2009. PMID: 19245695 Free PMC article. Review.
Cited by
-
Catastrophic antiphospholipid syndrome presented with sudden renal failure and history of long-lasting psychosis and hypertension in a 42 years old women.J Nephropathol. 2013 Apr;2(2):110-3. doi: 10.12860/JNP.2013.18. Epub 2013 Apr 1. J Nephropathol. 2013. PMID: 24475436 Free PMC article. No abstract available.
References
-
- Heilmann L, Schorsch M, Hahn T, Fareed J. Antiphospholipid syndrome and pre-eclampsia. Semin Thromb Hemost. 2011;37:141–145. - PubMed
-
- Asherson RA, Galarza-Maldonado C, Sanin-Blair J. The HELLP syndrome, antiphospholipid antibodies, and syndromes. Clin Rheumatol. 2008;27:1–4. - PubMed
-
- Sinha J, Chowdhry I, Sedan S, Barland P. Bone marrow necrosis and refractory HELLP syndrome in a patient with catastrophic antiphospholipid antibody syndrome. J Rheumatol. 2002;29:195–197. - PubMed
-
- Madan R, Khoursheed M, Kukla R, al-Mazidi M, Behbehani A. The anaesthetist and the antiphospholipid syndrome. Anaesthesia. 1997;52:72–76. - PubMed
LinkOut - more resources
Full Text Sources
Miscellaneous