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. 2012 Jun;62(6):575-8.
doi: 10.4097/kjae.2012.62.6.575. Epub 2012 Jun 19.

Anesthetic management of HELLP syndrome complicating primary antiphospholipid syndrome -A case report-

Youn Yi Jo  1 , Kyung Cheon Lee, Hong Soon Kim, Hyun Kyung Bae, Young Jin Chang
Affiliations

Anesthetic management of HELLP syndrome complicating primary antiphospholipid syndrome -A case report-

Youn Yi Jo et al. Korean J Anesthesiol. 2012 Jun.

Abstract

Antiphospholipid syndrome (APS) is defined as an autoimmune disorder characterized by recurrent thrombosis or obstetrical morbidity. A 29-year-old woman who was diagnosed with APS underwent emergency cesarean delivery at 23 weeks' gestation. She had a seizure attack and her laboratory findings were: AST/ALT 1459/1108 IU/L, LDH 1424 IU/L, 30% hematocrit, a platelet count of 43 × 10(3)/ml and urine protein (4+). We describe the anesthetic experience of catastrophic HELLP syndrome with antiphospholipid syndrome and we review the relevant literature.

Keywords: Antiphospholipid syndrome; Eclampsia; HELLP.

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References

    1. Le Thi Thuong D, Tieulie N, Costedoat N, Andreu MR, Wechsler B, Vauthier-Brouzes D, et al. The HELLP syndrome in the antiphospholipid syndrome: retrospective study of 16 cases in 15 women. Ann Rheum Dis. 2005;64:273–278. - PMC - PubMed
    1. Heilmann L, Schorsch M, Hahn T, Fareed J. Antiphospholipid syndrome and pre-eclampsia. Semin Thromb Hemost. 2011;37:141–145. - PubMed
    1. Asherson RA, Galarza-Maldonado C, Sanin-Blair J. The HELLP syndrome, antiphospholipid antibodies, and syndromes. Clin Rheumatol. 2008;27:1–4. - PubMed
    1. Sinha J, Chowdhry I, Sedan S, Barland P. Bone marrow necrosis and refractory HELLP syndrome in a patient with catastrophic antiphospholipid antibody syndrome. J Rheumatol. 2002;29:195–197. - PubMed
    1. Madan R, Khoursheed M, Kukla R, al-Mazidi M, Behbehani A. The anaesthetist and the antiphospholipid syndrome. Anaesthesia. 1997;52:72–76. - PubMed

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