Antibiotic resistance of microbial strains isolated from Korean acne patients
- PMID: 22779738
- DOI: 10.1111/j.1346-8138.2012.01626.x
Antibiotic resistance of microbial strains isolated from Korean acne patients
Abstract
Over several decades, topical and systemic antibiotics have been the mainstay of treatment for acne vulgaris. The widespread and long-term use of antibiotics in the treatment of acne has resulted in the spread of resistant bacterial strains and treatment failure. We aimed to examine the bacteriology of acne vulgaris and to evaluate its susceptibility to the antibiotics widely used for acne in Korea. We examined the species of bacteria aerobically and anaerobically isolated from 100 Korean acne patients. Among the bacteria isolated, Staphylococcus epidermidis (36 patients) was the most common, followed by Propionibacterium acnes (30 patients). Eleven strains of P. acnes (36.7%) and 25 strains of S. epidermidis (69.4%) were resistant to one or other of the antibiotics tested. A higher proportion of P. acnes isolates were resistant to clindamycin (30%) and erythromycin (26.7%), than to any other antibiotics tested (P = 0.0003). Some S. epidermidis isolates were resistant to tetracycline and doxycycline in addition to clindamycin and erythromycin. In the previous studies, few strains of P. acnes were found to be resistant to any of the antibiotics, but this study shows that antibiotic-resistant strains have been increasing in Korea acne patients.
© 2012 Japanese Dermatological Association.
Similar articles
-
Antibiotic susceptibility of Propionibacterium acnes isolated from acne vulgaris in Korea.J Dermatol. 2011 Jul;38(7):667-73. doi: 10.1111/j.1346-8138.2010.01109.x. Epub 2010 Nov 26. J Dermatol. 2011. PMID: 21352337
-
The bacteriology of acne vulgaris and antimicrobial susceptibility of Propionibacterium acnes and Staphylococcus epidermidis isolated from acne lesions.J Dermatol. 2000 May;27(5):318-23. doi: 10.1111/j.1346-8138.2000.tb02174.x. J Dermatol. 2000. PMID: 10875198
-
Antimicrobial susceptibility of Propionibacterium acnes isolates from acne patients in Colombia.Int J Dermatol. 2013 Jun;52(6):688-92. doi: 10.1111/j.1365-4632.2011.05403.x. Epub 2013 Mar 3. Int J Dermatol. 2013. PMID: 23451873
-
Acne and Propionibacterium acnes.Clin Dermatol. 2004 Sep-Oct;22(5):375-9. doi: 10.1016/j.clindermatol.2004.03.005. Clin Dermatol. 2004. PMID: 15556721 Review.
-
Antibiotic resistance in the topical treatment of acne vulgaris.Cutis. 2004 Jun;73(6 Suppl):6-10. Cutis. 2004. PMID: 15228128 Review.
Cited by
-
A review of diagnosis and treatment of acne in adult female patients.Int J Womens Dermatol. 2017 Dec 23;4(2):56-71. doi: 10.1016/j.ijwd.2017.10.006. eCollection 2018 Jun. Int J Womens Dermatol. 2017. PMID: 29872679 Free PMC article. Review.
-
Antibiotics and Antimicrobial Resistance in Acne: Epidemiological Trends and Clinical Practice Considerations.Yale J Biol Med. 2022 Dec 22;95(4):429-443. eCollection 2022 Dec. Yale J Biol Med. 2022. PMID: 36568833 Free PMC article. Review.
-
Recent advances in understanding Propionibacterium acnes ( Cutibacterium acnes) in acne.F1000Res. 2018 Dec 19;7:F1000 Faculty Rev-1953. doi: 10.12688/f1000research.15659.1. eCollection 2018. F1000Res. 2018. PMID: 30613388 Free PMC article. Review.
-
Association of Antimicrobial Susceptibility and Treatment Outcome in Acne Vulgaris Patients: A Pilot Study.J Lab Physicians. 2020 Dec;12(4):233-238. doi: 10.1055/s-0040-1720943. Epub 2020 Dec 30. J Lab Physicians. 2020. PMID: 33469248 Free PMC article.
-
The Antibiotic Susceptibility Profile of Cutibacterium Acnes in Maltese Patients with Acne.J Clin Aesthet Dermatol. 2020 Jun;13(6):11-16. Epub 2020 Jun 1. J Clin Aesthet Dermatol. 2020. PMID: 32884613 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical