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. 2012 Aug 21;48(65):8093-5.
doi: 10.1039/c2cc33477a. Epub 2012 Jul 10.

Fully automated sequential solid phase approach towards viral RNA-nucleopeptides

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Fully automated sequential solid phase approach towards viral RNA-nucleopeptides

Gerbrand J van der Heden van Noort et al. Chem Commun (Camb). .

Abstract

The synthesis of two ribonucleoprotein fragments of unprecedented complexity is reported. These hybrid biomolecules are prepared combining the use of an automated solid phase peptide and oligonucleotide synthesizer on a single solid support.

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