Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population
- PMID: 22783291
- PMCID: PMC3390085
- DOI: 10.3724/SP.J.1263.2011.00088
Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population
Abstract
Background: To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population.
Methods: The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed.
Results: The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 % and 34.7 %, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%, respectively).
Conclusions: Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications.
Keywords: ACE inhibitors; angiotensin receptor; heart failure; prognosis; β-blockers.
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