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. 2012 Jan;3(1):11-3.
Epub 2012 May 3.

Eosinophilic ulcer of oral mucosa: a case report

Marcelo Carlos Bortoluzzi  1 , Fabrício Passador-Santos, Diogo L Capella, Gabriel Manfro, Rudy José Nodari Jr, Andréia Antoniuk Presta
Affiliations

Eosinophilic ulcer of oral mucosa: a case report

Marcelo Carlos Bortoluzzi et al. Ann Stomatol (Roma). 2012 Jan.

Abstract

Eosinophilic Ulcer (EU) is a rare self-limiting chronic benign lesion of the oral mucosa with pathogenesis still unclear, however it may resemble malignancies, traumatic ulcerations and some infections such as deep fungal infections, tuberculosis and primary syphilis. This is a case report of a patient with EU in the lateral border of the tongue with no history of associated trauma and refractory to treatment with drugs. The ulcer rapidly healed after an incisional biopsy and the definite diagnosis was achieved only combining histologic findings and the clinical follow-up.

Keywords: eosinophilic ulcer; oral mucosa; ulcerative eosinophilic granuloma.

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Figures

Fig. 1
Fig. 1
Initial clinical aspect of the eosinophilic ulcer.
Fig. 2
Fig. 2
Clinical aspect of the lesion following the incisional biopsy.
Fig. 3
Fig. 3
Histopathological aspect of the tongue lesion. Notice that the infiltrate extends from the ulcer base deep into subjacent skeletal muscle (H&E; 100x).
Fig. 4
Fig. 4
Final aspect of the tongue.
See this image and copyright information in PMC

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