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Case Reports
. 2012 Apr;29(2):144-6.
doi: 10.4103/0970-9371.97162.

FNA diagnosis of CD99 positive neuroblastoma: A diagnostic dilemma

Gagandeep Kaur  1 , Pooja Bakshi, Kusum Verma
Affiliations
Case Reports

FNA diagnosis of CD99 positive neuroblastoma: A diagnostic dilemma

Gagandeep Kaur et al. J Cytol. 2012 Apr.

Abstract

Tissue diagnosis of small round cell tumors relies heavily on immunohistochemical staining. Two of the small round cell tumors, namely neuroblastoma and primitive neuroectodermal tumor, have considerable morphologic overlap. Many studies suggest that CD99 positivity virtually excludes the diagnosis of neuroblastoma. We report a case of poorly differentiated neuroblastoma in which aberrant CD99 positivity led to diagnostic dilemma.

Keywords: CD 99; neuroblastoma; primitive neuroectodermal tumor.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
(a) Smears showing occasional rossetting (MGG, ×400); (b) CD99 positivity on biopsy (IHC, ×400)
See this image and copyright information in PMC

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